Important Role of Fibronectin in the Extracellular Matrix
The extracellular matrix is an important network in our bodies, and fibronectin plays many roles in cell growth, migration, differentiation, and adhesion. Fibronectin is assembled in cells to form the extracellular matrix, which is a thick and specialized network that maintains tissue structure and functions. In vertebrate organisms, fibronectin is a crucial component in the formation of cartilage, skin, bones, and cartilage tissues. fibronectin Fibronectin is a protein that forms a fibrillar network when it interacts with receptors on cell surfaces. It is synthesized by various cells and secreted in large amounts as a disulfide-bonded dimer. Its structure consists of three modular consensus amino acid sequences with a variable region and extra domain A. The extra domains determine the dimer solubility and proteolysis susceptibility of fibronectin . Several studies have shown that fibronectin can bind to various target cells in different tissues. Studies have shown that fibronectin can